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It is important to note that the Fab-bound conformations may be different from the peptide agonist-bound conformations and that the ligand-bound forms may be different from the apo-form as suggested previously for GCGR 22

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Seek medical attention if nausea persists for more than two weeks, causes significant weight loss, or accompanies concerning symptoms like blood in stool, severe abdominal pain, or jaundice